Femke van Hout The last decade marks the exciting revolution of CRISPR/Cas9 genome editing. While the revolution still continues with further development and refinement of the Cas9 systems, the first patients are already receiving Cas9-based treatments. The Cas9 enzyme is a so-called “RNA-guided DNA nuclease”. This means that Cas9 is directed by RNA, the guide RNA, to find and cut the complementary target DNA. As this cutting mechanism is very precise and programmable, Cas9 can in theory be … [Lees meer...]
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